FXYD7 Rabbit Polyclonal Antibody

CAT#: TA319936

Rabbit Polyclonal FXYD7 Antibody

Product Images

Western blot analysis of FXYD7 in human lung tissue lysate with FXYD7 antibody at 1 ug/mL.

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  Immunohistochemistry of FXYD7 in rat lung tissue with FXYD7 antibody at 2.5 ug/mL.

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  Immunofluorescence of FXYD4 in rat lung tissue with FXYD4 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: FXYD7 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human FXYD7.
• Formulation: FXYD7 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: FXYD7 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: FXYD domain containing ion transport regulator 7
• Database Link:
  NP_071289
  Entrez Gene 57780 MouseEntrez Gene 63848 RatEntrez Gene 53822 Human
  UniProt ID P58549
• Background: FXYD7 Antibody: FXYD7 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing seven invariant and six highly conserved amino acids. The FXYD proteins are tissue-specific regulators of Na, K-ATPase, with FXYD7 initially identified as a brain-specific member. FXYD7 interacts with Na, K-ATPase through its transmembrane domain and is thought to influence the affinity of Na, K-ATPase for external K+ and Na+ ions. Other members of the FXDY family have similar functions: FXYD2 regulates the properties of Na, K-ATPase, while FXYD1 (phospholemman), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems.
• Synonyms: FLJ25096

Reference Data

• Protein Families: Ion Channels: Other, Transmembrane