MYCT1 Rabbit Polyclonal Antibody

CAT#: TA320027

Rabbit Polyclonal MYCT1 Antibody

Product Images

Western blot analysis of MYCT1 in rat lung tissue lysate with MYCT1 antibody at (A) 1 and (B) 2 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1.
• Formulation: MYCT1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: MYCT1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 26 kDa
• Gene Name: myc target 1
• Database Link:
  NP_079383
  Entrez Gene 68632 MouseEntrez Gene 292264 RatEntrez Gene 80177 Human
  UniProt ID Q8N699
• Background: MYCT1 Antibody: MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
• Synonyms: MTLC

Reference Data

• Protein Families: Transmembrane