Ltbr Rat Monoclonal Antibody [Clone ID: eBio3C8 (3C8)]

CAT#: TA320416

Rat Anti-Mouse Lymphotoxin beta Receptor Purified (100 ug)

Product Images

TA320416 antibody was tested by flow cytometric analysis of NIH/3T3 cells.

Specifications

Product Data

• Clone Name: eBio3C8 (3C8)
• Applications: FC
• Recommended Dilution: Flow
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: lymphotoxin B receptor
• Database Link:
  NP_034866
  Entrez Gene 17000 Mouse
  UniProt ID P50284
• Background: The antibody reacts with mouse lymphotoxin-beta receptor (LTBR). Northern blot analysis of tissues from adult mice showed that expression levels of LTBR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. The tumor necrosis factor receptor-related protein is the human receptor for the heterotrimer of lymphotoxin-alpha and lymphotoxin-beta. This LT-alpha/LT-beta heterotrimer (LT-α1β2) is assumed to take part in immunologic reactions by cell-cell contact, but does not bind to either TNFR1 (CD120α) or TNFR2 (CD120β). LTBR is expressed by day 7 embryos, so it has been speculated that the LT-alpha/LT-beta receptor system may also have some function in early embryogenesis.
• Synonyms: CD18; D12S370; LT-BETA-R; TNF-R-III; TNF-RIII; TNFCR; TNFR-III; TNFR-RP; TNFR2-RP; TNFR3; TNFRSF3