Slamf1 Rat Monoclonal Antibody [Clone ID: 9D1]

CAT#: TA320462

Rat Anti-Mouse CD150 Purified (100 ug)

Product Images

Staining of C57BL/6 splenocytes with 0.5 ug of Rat IgG1 kappa Isotype Control Purified (open histogram) or 0.5 ug of Anti-Mouse CD150 Purified (filled histogram) followed by Anti-Rat IgG Biotin and Streptavidin PE. Cells in the lymphocyte gate were used for analysis.

Specifications

Product Data

• Clone Name: 9D1
• Applications: FC
• Recommended Dilution: Flow, Functional Assay
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: signaling lymphocytic activation molecule family member 1
• Database Link:
  NP_038758
  Entrez Gene 27218 Mouse
  UniProt ID Q9QUM4
• Background: The 9D1 monoclonal antibody reacts with mouse CD150, an ~70 kDa transmembrane glycoprotein also known as Signaling Lymphocyte Activation Molecule (SLAM). CD150 is expressed by T (especially TH1) and B cells and its expression is rapidly upregulated on these cells upon activation. Immature thymocytes and dendritic cells also express this antigen. Signaling through SLAM in T cells induces proliferation and augmentation of the interferon-gamma response. Furthermore, SLAM is thought to play a role in adhesion between the T cell and antigen-presenting cell. 9D1 is reported to be an activating antibody.Mouse hematopoietic stem cells (HSC) can be identified using SLAM family markers, such as CD150+CD244-CD48-. For this application we recommend the use of antibody clone mShad150 (cat. 12-1502).
• Synonyms: CD150; CDw150; IPO-3; SLAM