SPO11 Goat Polyclonal Antibody

CAT#: TA321020

Goat Polyclonal Anti-SPO11 Antibody


USD 375.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications WB
Recommended Dilution WB: 1-3µg/ml
Reactivities Human
Host Goat
Clonality Polyclonal
Immunogen internal region of NP_036576.1; NP_937998.1 (NTYATKRDIYYTDSQ)
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name SPO11, initiator of meiotic double stranded breaks
Background Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq, Jul 2008]
Synonyms CT35; SPATA43; TOPVIA
Note This antibody is expected to recognize both reported isoforms (NP_036576.1; NP_937998.1)
Reference Data
Protein Families Druggable Genome, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.