Sodium Iodide Symporter (SLC5A5) Rabbit Polyclonal Antibody

CAT#: TA321131

Anti-SLC5A5 rabbit polyclonal antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: LOVO cell lysate
  IHC: 40-200
  Positive control: Human esophagus cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 1-14 amino acids of Human solute carrier family 5 (sodium iodide symporter), member 5
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 69 kDa
• Gene Name: solute carrier family 5 member 5
• Database Link:
  NP_000444
  Entrez Gene 114479 MouseEntrez Gene 114613 RatEntrez Gene 6528 Human
  UniProt ID Q92911
• Background: This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.
• Synonyms: NIS; TDH1

Reference Data

• Protein Families: Druggable Genome, Transmembrane