Sodium Iodide Symporter (SLC5A5) Rabbit Polyclonal Antibody

CAT#: TA321132

Anti-SLC5A5 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-2: Human colon tissue Human ovarian cancer tissue Primary antibody: TA321132 (SLC5A5 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 seconds

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA321132 (SLC5A5 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA321132 (SLC5A5 Antibody) at dilution 1/25, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human colon and ovarian cancer tissue
  IHC: 15-50
  Positive control: Human esophagus cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 1-14 amino acids of Human solute carrier family 5 (sodium iodide symporter), member 5
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 69 kDa
• Gene Name: solute carrier family 5 member 5
• Database Link:
  NP_000444
  Entrez Gene 114479 MouseEntrez Gene 114613 RatEntrez Gene 6528 Human
  UniProt ID Q92911
• Background: This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.
• Synonyms: NIS; TDH1

Reference Data

• Protein Families: Druggable Genome, Transmembrane