VMAT2 (SLC18A2) Rabbit Polyclonal Antibody

CAT#: TA321553

Anti-SLC18A2 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human cervical cancer tissue
  IHC: 25-100
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 500-514 amino acids of human solute carrier family 18 (vesicular monoamine), member 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55 kDa
• Gene Name: solute carrier family 18 member A2
• Database Link:
  NP_003045
  Entrez Gene 25549 RatEntrez Gene 214084 MouseEntrez Gene 6571 Human
  UniProt ID Q05940
• Background: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles; using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs; including reserpine and tetrabenazine .
• Synonyms: SVAT; SVMT; VAT2; VMAT2

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Parkinson's disease