ACTR1A Rabbit Polyclonal Antibody

CAT#: TA321723

Anti-ACTR1A Rabbit Polyclonal Antibody

Product Images

Predicted band size: 43 kDa. Positive control: MCF7 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1000-2000, WB: 1:200-1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 250 amino acids of human ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 43 kDa
• Gene Name: ARP1 actin-related protein 1 homolog A, centractin alpha
• Database Link:
  NP_005727
  Entrez Gene 54130 MouseEntrez Gene 294010 RatEntrez Gene 10121 Human
  UniProt ID P61163
• Background: This gene encodes a 42.6 kD subunit of dynactin; a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions; including ER-to-Golgi transport; the centripetal movement of lysosomes and endosomes; spindle formation; chromosome movement; nuclear positioning; and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule; and is the most abundant molecule in the dynactin complex. It is an actin-related protein; and is approximately 60% identical at the amino acid level to conventional actin.
• Synonyms: ARP1; Arp1A; CTRN1