MIDN Rabbit Polyclonal Antibody

CAT#: TA322004

Anti-MIDN Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human lung tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 2-19 amino acids of Human midnolin
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 49 kDa
• Gene Name: midnolin
• Database Link:
  NP_796375
  Entrez Gene 59090 MouseEntrez Gene 314623 RatEntrez Gene 90007 Human
  UniProt ID Q504T8
• Background: Expression of the?midnolin?gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. The?midnolin?encodes a protein of 508 amino acids (aa); which contains a Ubiquitin-like domain. The intracellular distribution of the?midnolin?was studied by using?midnolin-green fluorescent protein (GFP) fusion proteins.?Midnolin?was found to be localized in the nucleus and nucleolus; but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the?midnolin.?May be involved in regulation of genes related to neurogenesis in the nucleolus
• Synonyms: DKFZp547M072

Reference Data

• Protein Families: Druggable Genome