MAFF Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 25-100 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 76-84 amino acids of Human v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 18 kDa |
Gene Name | MAF bZIP transcription factor F |
Database Link | |
Background | The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers; and since it lacks a transactivation domain; the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. |
Synonyms | hMafF; U-MAF |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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