MERTK Rabbit Polyclonal Antibody

CAT#: TA322506

Anti-MERTK Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 100-300
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 300 amino acids of human c-mer proto-oncogene tyrosine kinase
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: MER proto-oncogene, tyrosine kinase
• Database Link:
  NP_006334
  Entrez Gene 17289 MouseEntrez Gene 65037 RatEntrez Gene 10461 Human
  UniProt ID Q12866
• Background: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains; two Ig-like C2-type (immunoglobulin-like) domains; and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
• Synonyms: c-mer; MER; RP38

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane