RHEB Rabbit Polyclonal Antibody
Other products for "RHEB"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 50-200 Positive control: Human brain Predicted cell location: Cytoplasm |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 150-162 amino acids of Human Ras homolog enriched in brain |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | Ras homolog enriched in brain |
Database Link | |
Background | This gene is a member of the small GTPase superfamily and encodes a lipid-anchored; cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form; and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped; two on chromosome 10 and one on chromosome 22. |
Synonyms | RHEB2 |
Reference Data | |
Protein Pathways | Insulin signaling pathway, mTOR signaling pathway |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.