IGFBP3 Rabbit Polyclonal Antibody

CAT#: TA323616

Anti-IGFBP3 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 24-41 kDa. Positive control: HepG2, 3T3, Hela, 293, Jurkat, K562, Raji cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane 1, 2, 3, 4, 5, 6, 7: HepG2, 3T3, Hela, 293, Jurkat, K562, Raji cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide sequence around aa.185~189(R-Y-K-V-D) derived from Human IGFBP-3.
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: insulin like growth factor binding protein 3
• Database Link:
  NP_000589
  Entrez Gene 3486 Human
  UniProt ID P17936
• Background: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
• Synonyms: BP-53; IBP3

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: p53 signaling pathway