Carbonic Anhydrase I (CA1) Rabbit Polyclonal Antibody

CAT#: TA323826

Anti-CA1 Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 24 μg Lane: Mouse liver tissue Primary antibody: TA323826 (CA1 Antibody) at dilution 1/450 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse liver tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 29 kDa
• Gene Name: carbonic anhydrase 1
• Database Link:
  NP_001122301
  Entrez Gene 759 Human
  UniProt ID P00915
• Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes; including respiration; calcification; acid-base balance; bone resorption; and the formation of aqueous humor; cerebrospinal fluid; saliva; and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8; and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants; encoding the same protein; have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.
• Synonyms: CA-I; CAB; Car1; HEL-S-11

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Nitrogen metabolism