ErbB 4 (ERBB4) Rabbit Polyclonal Antibody

CAT#: TA324770

Rabbit polyclonal Phospho-HER4(Y1162) Antibody

Product Images

Phospho-HER4-Y1162 Antibody (cat# TA324770)was used to detect Phospho-HER4-Y1162 in FG pancreatic carcinoma cell line lysate.

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  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

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  Confocal immunofluorescent analysis of Phospho-HER4-Y1162 Antibody (Cat#TA324770) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1:1000, IHC: 1:50~100, IF: 1:10~50
• Reactivities: Human
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: This HER4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1162 of human HER4.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 146808 Da
• Gene Name: erb-b2 receptor tyrosine kinase 4
• Database Link:
  NP_005226
  Entrez Gene 13869 MouseEntrez Gene 59323 RatEntrez Gene 2066 Human
  UniProt ID Q15303
• Synonyms: ALS19; HER4; p180erbB4

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Calcium signaling pathway, Endocytosis, ErbB signaling pathway