Alpha 1 Acid Glycoprotein (ORM1) Rabbit Polyclonal Antibody

CAT#: TA327179

Rabbit anti-ORM1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using ORM1 antibody.

• 

  Immunohistochemistry of paraffin-embedded human kidney using ORM1 antibody at dilution of 1:200 (200x lens).

• 

  Immunohistochemistry of paraffin-embedded mouse esophagus using ORM1 antibody at dilution of 1:200 (200x lens).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human ORM1
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: orosomucoid 1
• Database Link:
  NP_000598
  Entrez Gene 18405 MouseEntrez Gene 5004 Human
  UniProt ID P02763
• Background: Alpha-1-acid glycoprotein 1 (AGP1), also called orosomucoid-1 (ORM1), is a glycoprotein synthesized mostly by hepatocytes and present in human plasma. ORM1 is an acute-phase reactant protein controlled by glucocorticoids, interleukin-1 and interleukin-6, and increase up to 5-50 times upon infection and/or inflammation. Anti-apoptotic effect and role as immunomodulator of ORM have been reported. ORM is an important carrier for synthetic drugs and influences their distribution and availability in the body. This antibody recognizes a band about 44 kDa in human plasma which may be due to the glycosylation of ORM1 or the dimer formation of the protein.
• Synonyms: AGP-A; AGP1; HEL-S-153w; ORM

Reference Data

• Protein Families: Druggable Genome, Secreted Protein