Macro H2A.2 (H2AFY2) Rabbit Polyclonal Antibody

CAT#: TA328139

Rabbit polyclonal anti-H2AFY2 antibody (Center)

Product Images

H2AFY2 Antibody (Center) (Cat. #TA328139) western blot analysis in CEM, NCI-H460 cell line lysates (35ug/lane).This demonstrates the H2AFY2 antibody detected the H2AFY2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This H2AFY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-169 amino acids from the Central region of human H2AFY2.
• Formulation: PBS with 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: H2A histone family member Y2
• Database Link:
  NP_061119
  Entrez Gene 55506 Human
  UniProt ID Q9P0M6
• Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
• Synonyms: macroH2A2

Reference Data

• Protein Pathways: Systemic lupus erythematosus