MGMT Mouse Monoclonal Antibody [Clone ID: 888CT22.2.4]

CAT#: TA328166

Mouse monoclonal anti-MGMT antibody(Ascites)

Product Images

MGMT Antibody (Cat. #TA328166) western blot analysis in MCF-7, Jurkat, Hela cell line lysates (35ug/lane).This demonstrates the MGMT antibody detected the MGMT protein (arrow).

Specifications

Product Data

• Clone Name: 888CT22.2.4
• Applications: WB
• Recommended Dilution: WB: 1:2000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified His-tagged MGMT protein was used to produced this monoclonal antibody.
• Formulation: crude ascites with 0.09% (W/V) sodium azide
• Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: O-6-methylguanine-DNA methyltransferase
• Database Link:
  NP_002403
  Entrez Gene 4255 Human
  UniProt ID P16455
• Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
• Synonyms: methylguanine-DNA methyltransferase; O-6-methylguanine-DNA methyltransferase; O6-methylguanine-DNA methyltransferase; OTTHUMP00000020741

Reference Data

• Protein Families: Druggable Genome