SRCAP Goat Polyclonal Antibody
Other products for "SRCAP"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 5-10ug/ml |
Reactivities | Human |
Host | Goat |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Peptide with sequence C-QEGNDAEAQRREIE, from the internal region (near N Trminus) of the protein sequence according to NP_006653.2 |
Formulation | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Concentration | lot specific |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | Snf2-related CREBBP activator protein |
Database Link | |
Background | This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features. [provided by RefSeq, Feb 2012] |
Synonyms | DOMO1; EAF1; FLHS; SWR1 |
Note | IHC: In paraffin embedded Human Skin shows nuclear staining in some keratinocytes. |
Reference Data |
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