PDK4 Rabbit Polyclonal Antibody

CAT#: TA331166

Rabbit Polyclonal Anti-PDK4 Antibody

Product Images

WB Suggested Anti-PDK4 Antibody Titration: 0.2-1 ug/ml; Positive Control: Transfected 293T

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  Sample Type: Huh7 HepG2 (50ug); Primary Antibody Dilution: 1:500 ; Image Submitted By: Partha Kasturi; University of Kansas Medical Center

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  Human Muscle

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB, IHC
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-PDK4 antibody: synthetic peptide directed towards the N terminal of human PDK4. Synthetic peptide located within the following region: MKAARFVLRSAGSLNGAGLVPREVEHFSRYSPSPLSMKQLLDFGSENACE
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 46 kDa
• Gene Name: pyruvate dehydrogenase kinase 4
• Database Link:
  NP_002603
  Entrez Gene 5166 Human
  UniProt ID Q16654
• Background: PDK4 is a member of the PDK/BCKDK protein kinase family and is a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism.This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
• Synonyms: FLJ40832
• Note: Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 100%; Dog: 92%; Rat: 92%; Mouse: 92%; Bovine: 92%; Guinea pig: 92%

Reference Data

• Protein Families: Druggable Genome, Protein Kinase