Cannabinoid Receptor I Rabbit Polyclonal Antibody

CAT#: TA332399

Rabbit anti-CNR1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of mouse brain tissue lines, using CNR1 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CNR1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 472
• Database Link:
  Entrez Gene 12801 MouseEntrez Gene 25248 Rat
• Background: This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. _
• Synonyms: CANN6; cannabinoid receptor 1 (brain); CB-R; CB1; CB1A; CB1K5; CB1R; central cannabinoid receptor; CNR; OTTHUMP00000016838; OTTHUMP00000016839; OTTHUMP00000016840

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction