CD105 (ENG) Rabbit Polyclonal Antibody

CAT#: TA332807

Rabbit anti-ENG Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using ENG antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human ENG
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 658
• Gene Name: endoglin
• Database Link:
  NP_000109
  Entrez Gene 13805 MouseEntrez Gene 2022 Human
  UniProt ID P17813
• Background: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: END; HHT1; ORW1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane