STAT2 Rabbit Polyclonal Antibody

CAT#: TA333143

Phospho-STAT2-Y690 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts from Hela cells using Phospho-STAT2-Y690 antibody.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB,1:100 - 1:500
  ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 98kDa
• Gene Name: signal transducer and activator of transcription 2
• Database Link:
  NP_005410
  Entrez Gene 20847 MouseEntrez Gene 288774 RatEntrez Gene 6773 Human
  UniProt ID P52630
• Background: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44.
• Synonyms: IMD44; ISGF-3; P113; STAT113

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Chemokine signaling pathway, Jak-STAT signaling pathway