Sodium Iodide Symporter (SLC5A5) Rabbit Polyclonal Antibody

CAT#: TA334165

Rabbit Polyclonal Anti-SLC5A5 Antibody

Product Images

WB Suggested Anti-SLC5A5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: 293T cell lysate;SLC5A5 is supported by BioGPS gene expression data to be expressed in HEK293T

• 

  Host: Rabbit; Target Name: SLC5A5; Sample Tissue: 293T; Antibody Dilution: 1.0 ug/ml; SLC5A5 is supported by BioGPS gene expression data to be expressed in HEK293T

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for Anti-SLC5A5 Antibody: synthetic peptide directed towards the middle region of human SLC5A5. Synthetic peptide located within the following region: PSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRP
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 69 kDa
• Gene Name: solute carrier family 5 member 5
• Database Link:
  NP_000444
  Entrez Gene 6528 Human
  UniProt ID Q92911
• Background: The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones.The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones (Dohan et al., 2007 [PubMed 18077370]). [supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Synonyms: NIS; TDH1
• Note: Immunogen sequence homology: Human: 100%

Reference Data

• Protein Families: Druggable Genome, Transmembrane