FKBP25 (FKBP3) Rabbit Polyclonal Antibody

CAT#: TA335027

Rabbit Polyclonal Anti-FKBP3 Antibody

Product Images

WB Suggested Anti-FKBP3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysateFKBP3 is supported by BioGPS gene expression data to be expressed in Jurkat

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  Host: Rabbit; Target Name: FKBP3; Sample Tissue: Human MCF7; Antibody Dilution: 1.0 ug/ml; FKBP3 is supported by BioGPS gene expression data to be expressed in MCF7

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  Host: Rabbit; Target Name: FKBP3; Sample Tissue: Human 721_B; Antibody Dilution: 1.0 ug/ml; FKBP3 is supported by BioGPS gene expression data to be expressed in 721_B

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  Host: Rabbit; Target Name: FKBP3; Sample Tissue: Human Hela; Antibody Dilution: 1.0 ug/ml; FKBP3 is supported by BioGPS gene expression data to be expressed in HeLa

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-FKBP3 antibody: synthetic peptide directed towards the C terminal of human FKBP3. Synthetic peptide located within the following region: EALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: FK506 binding protein 3
• Database Link:
  NP_002004
  Entrez Gene 2287 Human
  UniProt ID Q00688
• Background: FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
• Synonyms: FKBP-3; FKBP-25; FKBP25; PPIase
• Note: Immunogen Sequence Homology: Dog: 100%; Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Rabbit: 100%; Guinea pig: 100%; Zebrafish: 93%

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency