FIP1L1 Rabbit Polyclonal Antibody

CAT#: TA343940

Rabbit Polyclonal Anti-FIP1L1 Antibody

Product Images

WB Suggested Anti-FIP1L1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate; FIP1L1 is supported by BioGPS gene expression data to be expressed in Jurkat

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  Rabbit Anti-FIP1L1 antibody; Paraffin Embedded Tissue: Human Brain cell; Cellular Data: Epithelial cells of renal tubule; Antibody Concentration: 4.0-8.0 ug/ml; Magnification: 400X

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-FIP1L1 antibody: synthetic peptide directed towards the C terminal of human FIP1L1. Synthetic peptide located within the following region: EYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGD
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 65 kDa
• Gene Name: factor interacting with PAPOLA and CPSF1
• Database Link:
  NP_112179
  Entrez Gene 81608 Human
  UniProt ID Q6UN15
• Background: FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. It binds to U-rich RNA sequence elements surrounding the poly(A) site. FIP1L1 may act to tether poly(A) polymerase to the CPSF complex.
• Synonyms: FIP1; hFip1; Rhe
• Note: Immunogen Sequence Homology: Dog: 100%; Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Guinea pig: 100%; Rabbit: 93%; Zebrafish: 86%