FKBP25 (FKBP3) Rabbit Polyclonal Antibody
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Recombinant protein of human FK506 binding protein 3, 25kDa (FKBP3)
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Specifications
Product Data | |
Applications | ELISA, WB |
Recommended Dilution | ELISA (1:100 ?? 1:200) ; Western blotting (1:500) |
Reactivities | Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-FKBP3 antibody: mouse FKBP3 (FK506 Binding Protein 3), using a KLH-conjugated synthetic peptide containing an amino acid sequence from the central part of the protein |
Concentration | lot specific |
Purification | Whole antiserum from rabbit containing 0.05% azide. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | FK506 binding protein 3 |
Database Link | |
Background | FKBP3 (UniProtKB/Swiss-Prot entry Q00688) is a member of the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It acts as a receptor for FK506 and rapamycin, two immunosuppressants which inhibit T-cell proliferation. FKBP3 localizes to the nucleus and interacts with the transcription factor YY1 and with histone deacetylases. Therefore, it may play a role in chromatin modification and be important for the regulation of transcription. |
Synonyms | FKBP-3; FKBP-25; FKBP25; PPIase |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency |
Documents
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