MBD4 Rabbit Polyclonal Antibody
Frequently bought together (2)
Transient overexpression lysate of methyl-CpG binding domain protein 4 (MBD4)
USD 605.00
Other products for "MBD4"
Specifications
Product Data | |
Applications | ELISA, WB |
Recommended Dilution | ELISA (1:100 ?? 1:1,000); Western blotting (1:2,000) |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-MBD4 antibody: human MBD4 (Methyl-CpG-binding domain protein 4), using three different KLH-conjugated synthetic peptides. |
Concentration | lot specific |
Purification | Whole antiserum from rabbit containing 0.05% azide. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | methyl-CpG binding domain 4, DNA glycosylase |
Database Link | |
Background | MBD4 (UniProt/Swiss-Prot entry O95243) belongs to the family of methyl CpG binding proteins that specifically bind to methylated CpG dinucleotides. MBD4 probably functions to mediate the biological consequences of CpG methylation. Further, MBD4 has thymine glycosylase activity and is involved in DNA repair. Mutations of MBD4 are associated with tumors with primary microsatellite-instability, a type of genomic instability that is caused by a defective DNA mismatch repair. |
Synonyms | MED1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Base excision repair |
Documents
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