TFE3 Rabbit Polyclonal Antibody

CAT#: TA347562

Rabbit Polyclonal Anti-TFE3 Antibody

Product Images

Western blot analysis on K562 cell lysate using TFE3 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-TFE3 Antibody: A synthesized peptide derived from human TFE3
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 62 kDa
• Gene Name: transcription factor binding to IGHM enhancer 3
• Database Link:
  NP_006512
  Entrez Gene 209446 MouseEntrez Gene 7030 Human
  UniProt ID P19532
• Background: TFE3 Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer.
• Synonyms: bHLHe33; RCCP2; RCCX1; TFEA
• Note: TFE3 antibody detects endogenous levels of total TFE3

Reference Data

• Protein Families: Druggable Genome, Transcription Factors