Shugoshin (SGO1) Rabbit Polyclonal Antibody

CAT#: TA347652

Rabbit Polyclonal Anti-SGOL1 Antibody

Product Images

Western blot analysis on HeLa cell lysate using SGOL1 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-SGOL1 Antibody: A synthesized peptide derived from human SGOL1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 64 kDa
• Gene Name: shugoshin 1
• Database Link:
  NP_612493
  Entrez Gene 151648 Human
  UniProt ID Q5FBB7
• Background: SGO1 Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase.
• Synonyms: CAID; NY-BR-85; SGO; SGOL1
• Note: SGOL1 Antibody detects endogenous levels of SGOL1

Reference Data

• Protein Pathways: Oocyte meiosis