POU2F3 Rabbit Polyclonal Antibody

CAT#: TA349054

Rabbit Polyclonal Anti-POU2F3 Antibody

Product Images

Western blot analysis of POU2F3 in SK-N-SH cell lysate with POU2F3 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of POU2F3 in rat brain tissue with POU2F3 antibody at 5 ug/mL.

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  Immunofluorescence of POU2F3 in rat brain tissue with POU2F3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: POU2F3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human POU2F3.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: POU2F3 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 48 kDa; Observed: 55 kDa
• Gene Name: POU class 2 homeobox 3
• Database Link:
  NP_055167
  Entrez Gene 18988 MouseEntrez Gene 116544 RatEntrez Gene 25833 Human
  UniProt ID Q9UKI9
• Background: POU2F3, also known as Epoc-1, is a member of a family of POU domain family of transcription factors (1). POU2F3 is expressed primarily in the epidermis and plays a critical role in keratinocyte proliferation and differentiation (1,2). It is a crucial transcription factor that is required for the development of sweet, umami, and bitter, but not sour taste receptor cells (3). POU2F3 is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer (4).
• Synonyms: Epoc-1; OCT-11; OCT11; OTF-11; PLA-1; PLA1; Skn-1a