NBL1 Rabbit Polyclonal Antibody
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Other products for "NBL1"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Nucleus |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human NBL1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | neuroblastoma 1, DAN family BMP antagonist |
Database Link | |
Background | This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. |
Synonyms | D1S1733E; DAN; DAND1; NB; NO3 |
Reference Data | |
Protein Families | Secreted Protein |
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