NUP62 Rabbit Polyclonal Antibody

CAT#: TA350241

Rabbit Polyclonal Anti-NUP62 Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela cells and human brain malignant glioma tissue, NIH/3T3, PC3 and A549 cells
  IHC: 50-200
  Positive control: Human prostate cancer
  Predicted cell location: Cytoplasm or Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human NUP62
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 53 kDa
• Gene Name: nucleoporin 62kDa
• Database Link:
  NP_714940
  Entrez Gene 18226 MouseEntrez Gene 65274 RatEntrez Gene 23636 Human
  UniProt ID P37198
• Background: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform.
• Synonyms: IBSN; p62; SNDI

Reference Data

• Protein Families: Druggable Genome, Transcription Factors