GPR124 (ADGRA2) Rabbit Polyclonal Antibody

CAT#: TA351229

Rabbit Polyclonal Anti-GPR124 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Rat urinary bladder tissue lysate Primary antibody: TA351229 (ADGRA2 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 5 minutes

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351229 (ADGRA2 Antibody) at dilution 1/50 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351229 (ADGRA2 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA351229 (ADGRA2 Antibody) at dilution 1/50 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA351229 (ADGRA2 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human GPR124
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 143 kDa
• Gene Name: adhesion G protein-coupled receptor A2
• Database Link:
  NP_116166
  Entrez Gene 78560 MouseEntrez Gene 100363275 RatEntrez Gene 25960 Human
  UniProt ID Q96PE1
• Background: TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
• Synonyms: GPR124; TEM5

Reference Data

• Protein Families: Druggable Genome, Transmembrane