RASGAP (RASA2) Rabbit Polyclonal Antibody

CAT#: TA351584

Rabbit Polyclonal Anti-RASA2 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Human bladder carcinoma tissue Primary antibody: TA351584 (RASA2 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 3 minutes

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse heart tissue, A172 and 231 cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human RASA2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 97 kDa
• Gene Name: RAS p21 protein activator 2
• Database Link:
  NP_006497
  Entrez Gene 5922 Human
  UniProt ID Q15283
• Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants.
• Synonyms: GAP1M

Reference Data

• Protein Pathways: MAPK signaling pathway