plk1 Mouse Monoclonal Antibody [Clone ID: AZ44]

CAT#: TA353387L

Mouse monoclonal Anti-Plx Clone AZ44

Specifications

Product Data

• Clone Name: AZ44
• Recommended Dilution: ELISA ; WB
• Reactivities: Xenopus
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Baculo expressed Polo-like-kinase from Xenopus laevis
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Background: Polo-like kinase (Plx) is a mitotic regulator conserved from yeasts to humans. Many key cell cycle regulators such as p53, cdc25, cyclin B and the Anaphase Promoting Complex are directly targeted by Plx.The Anaphase promoting complex is responsible for the destruction of cyclins and other proteins involved with mitosis.
• Note: Plx is activated by phosphorylation. AZ44 only detects the mitotic form of Plx (Xenopus laevis) which may be due to the recognition of a phosphorylated epitope. Recommended concentration: 1ug/ml