SIGLEC5 Mouse Monoclonal Antibody [Clone ID: 1A5]

CAT#: TA353462

Mouse monoclonal Anti-SIGLEC5 Clone 1A5

Specifications

Product Data

• Clone Name: 1A5
• Recommended Dilution: ELISA ; FACS ; IHC ; IF ; IP ; Functional ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Siglec-5-Fc protein, containing entire extracellular region of siglec-5 fused with the Fc region of human IgG1
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: sialic acid binding Ig like lectin 5
• Database Link:
  NP_003821
  Entrez Gene 8778 Human
  UniProt ID O15389
• Background: The Siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Siglec5 (CD170) is a member of the recently-described human CD33-related siglec subgroup of sialic acid binding Ig-like lectins and is expressed on myeloid cells of the hemopoietic system. Similar to other CD33- related siglecs, Siglec-5 contains two tyrosine based motifs in its cytoplasmic tails implicated in signalling functions. The antibody cross reacts with Siglec14.
• Synonyms: CD33L2; CD170; OB-BP2; OBBP2; SIGLEC-5

Reference Data

• Protein Families: Druggable Genome, Transmembrane