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Tyrosinase (TYR) Mouse Monoclonal Antibody [Clone ID: T311]
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Specifications
| Product Data | |
| Clone Name | T311 |
| Applications | IHC |
| Recommended Dilution | 1:50 |
| Reactivities | Human |
| Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Recombinant prokaryotic protein corresponding to the tyrosinase molecule |
| Specificity | Human tyrosinase |
| Formulation | Liquid tissue culture supernatant containing sodium azide as a preservative |
| Conjugation | Unconjugated |
| Storage | Store at 2-8°C |
| Stability | 12 months |
| Gene Name | tyrosinase |
| Database Link | |
| Background | The biosynthesis of melanin in melanocytes involves a family of enzymes, a key member of which is tyrosinase. Tyrosinase deficiency is associated with various forms of albinism and in particular oculocutaneous albinism. L-tyrosinase is the initial substrate for melanin biosynthesis and its conversion to dopaquinone is catalyzed by tyrosinase, whose expression is reported in melanocytes and melanomas. |
| Synonyms | LB24-AB; OCA1A; OCAIA; SHEP3; SK29-AB; tyrosinase |
| Reference Data | |
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