MARCH2 Rabbit Polyclonal Antibody

CAT#: TA356275

MARCH2 Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: MARCH2 Sample Type: Esophagus Tumor lysates Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MARCH2
• Specificity: Expected reactivity: Guinea Pig, Human, Rabbit
  Homology: Guinea Pig: 90%; Human: 100%; Rabbit: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 27kDa
• Gene Name: membrane associated ring-CH-type finger 2
• Database Link:
  NP_057580
  Entrez Gene 51257 Human
  UniProt ID Q9P0N8
• Background: MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking.
• Synonyms: HSPC240; MARCH-II; RNF172

Reference Data

• Protein Families: Druggable Genome, Transmembrane