ARFGAP3 Rabbit Polyclonal Antibody

CAT#: TA357981

ARFGAP3 Antibody - C-terminal region

Product Images

WB Suggested Anti-ARFGAP3 Antibody Titration: 0.125 ug/ml Positive Control: Fetal Lung

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Horse, Human, Pig, Rat
  Homology: Cow: 86%; Dog: 100%; Horse: 93%; Human: 100%; Pig: 79%; Rat: 86%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 57kDa
• Gene Name: ADP ribosylation factor GTPase activating protein 3
• Database Link:
  NP_055385
  Entrez Gene 26286 Human
  UniProt ID Q9NP61
• Background: The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
• Synonyms: ARFGAP1; FLJ45618

Reference Data

• Protein Pathways: Endocytosis