LILRB2 Rabbit Polyclonal Antibody

CAT#: TA358570

LILRB2 Antibody - C-terminal region

Product Images

WB Suggested Anti-LILRB2 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Brain

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  Host: Rabbit Target Name: LILRB2 Sample Tissue: Human HepG2 Whole Cell Antibody Dilution: 1ug/ml

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  Host: Rabbit Target: LILRB2 Positive control (+): Human brain (BR) Negative control (-): 293T (2T) Antibody concentration: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human
  Homology: Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 65kDa
• Gene Name: leukocyte immunoglobulin like receptor B2
• Database Link:
  NP_005865
  Entrez Gene 10288 Human
  UniProt ID Q8N423
• Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: CD85D; ILT-4; ILT4; LILRA6; LIR-2; LIR2; MIR-10; MIR10; OTTHUMP00000067358

Reference Data

• Protein Families: Transmembrane