CFHR4 Rabbit Polyclonal Antibody

CAT#: TA358864

CFHR4 Antibody - C-terminal region

Product Images

WB Suggested Anti-CFHR4 Antibody Titration: 1.0 ug/ml Positive Control: Placenta

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human
  Homology: Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 63kDa
• Gene Name: complement factor H related 4
• Database Link:
  NP_001188480
  Entrez Gene 10877 Human
  UniProt ID A8K9N7
• Background: This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.
• Synonyms: CFHL4; FHR-4; FHR4; RP4-608O15.2

Reference Data

• Protein Families: Secreted Protein