TFE3 Rabbit Polyclonal Antibody

CAT#: TA359735

TFE3 Antibody - middle region

Product Images

Host: Rabbit Target Name: TFE3 Sample Tissue: Human 293T Whole Cell lysates Antibody Dilution: 1ug/ml

• 

  Host: Mouse Target Name: TFE3 Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TFE3
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 63 kDa
• Gene Name: transcription factor binding to IGHM enhancer 3
• Database Link:
  NP_001269071.1
  Entrez Gene 7030 Human
  UniProt ID P19532
• Background: This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.
• Synonyms: bHLHe33; RCCP2; TFEA