NKG2C (KLRC2) Rabbit Polyclonal Antibody

CAT#: TA360142

KLRC2 Antibody - N-terminal region

Product Images

WB Suggested Anti-NKG2°C antibody Titration: 1 ug/mL Sample Type: Human Ovary Tumor

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen for Anti-KLRC2 antibody is: synthetic peptide directed towards the N-terminal region of Human NKG2C
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 25 kDa
• Gene Name: killer cell lectin like receptor C2
• Database Link:
  NP_002251.2
  Entrez Gene 3822 Human
  UniProt ID P26717
• Background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined.
• Synonyms: CD159c; MGC138244; NKG2-C; NKG2C