CHIT1 Rabbit Polyclonal Antibody

CAT#: TA361384

CHIT1 Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: CHIT1 Sample Tissue: Human Leiomyosarcoma Tumor lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CHIT1
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 51 kDa
• Gene Name: chitinase 1
• Database Link:
  NP_001243054.2
  Entrez Gene 1118 Human
  UniProt ID Q13231
• Background: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
• Synonyms: CHI3; CHIT; Chitinase-1; chitotriosidase; FLJ00314; MGC125322