PITRM1 Rabbit Polyclonal Antibody

CAT#: TA361761

PITRM1 Antibody - middle region

Product Images

Host: Rabbit Target Name: PITRM1 Sample Tissue: Human Ovary Tumor lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PITRM1
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 114 kDa
• Gene Name: pitrilysin metallopeptidase 1
• Database Link:
  NP_001229236.1
  Entrez Gene 10531 Human
  UniProt ID Q5JRX3
• Background: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.
• Synonyms: hMP1; hPreP; KIAA1104; MGC138192; MGC141929; MP1; PreP