POLDIP3 Rabbit Polyclonal Antibody

CAT#: TA365337

POLDIP3 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: TM4 cell Primary antibody: TA365337 (POLDIP3 Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: TM4 cell
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human POLDIP3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 46 kDa
• Database Link:
  UniProt ID Q9BY77
• Background: POLDIP3 (polymerase delta-interacting protein 3), also known as SKAR or PDIP46, is a 421 amino acid nuclear protein. POLDIP3 interacts with DNA pol ∂ 2, a protein essential to DNA replication, recombination and repair. POLDIP3 is a substrate for the signaling intermediate Rsk-1 and is thought to regulate cell growth. POLDIP3 contains one RRM (RNA recognition motif) domain and is phosphorylated upon DNA damage. POLDIP3 is ubiquitously expressed with highest levels found in heart, kidney, skeletal muscle and brain. Due to alternative splicing, POLDIP3 is expressed as two isoforms.