ESRP2 Rabbit Polyclonal Antibody

CAT#: TA368271

ESRP2 rabbit polyclonal antibody


USD 380.00

4 Weeks*

Size
    • 100 ul

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Other products for "ESRP2"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 200-1000
WB positive control: Human bladder transitional cell carcinoma grade 2-3 tissue lysate
IHC: 30-150
Positive control: Human lung cancer
Predicted cell location: Nucleus
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human ESRP2
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C.
Stability 1 year
Predicted Protein Size 78 kDa
Background mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.