CXXC5 Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 50-200 Positive control: Human tonsil Predicted cell location: Nucleus |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human CXXC5 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Database Link | |
Background | CXXC5 (CXXC finger 5), also known as RINF or HSPC195, is a 322 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one CXXC-type zinc finger. Interacting with Dvl-1, CXXC5 acts as a mediator of Wnt signaling in neural stem cells and is thought to participate in the activation of MAP kinase pathways. The gene encoding CXXC5 maps to human chromosome 5 and is expressed as multiple alternatively spliced isoforms. |
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